Seeking to boost student success in health sciences, Austin Community College’s (ACC) Biology Department set out to fundamentally change how students learn and master prerequisite course material. Faculty members re-designed three traditional lecture courses by introducing web-based modules and coupling them with class sessions devoted primarily to student-led, small group activities. Data reports from ACC show that an increasing proportion of students are choosing to enroll in the “flipped” versions of these classes and are succeeding at higher rates than traditional versions of the same classes.